Quattro QuikPrep™ / LabPrep™ CPC & CCC units: 250 to 2000ml total instrument volumes. Options of multiple volumes per instrument from 30ml. Price range £27,500 to £87,500.
To the above pricing for scale-up, must be added customised Ancillary Instrumentation:- Pumps, Detector, Fraction Collection, Control Computer Etc., to match your needs and budget. Or provide your own existing or new ancillary instrumentation.
Click any of the 4 slides to go to same slide show
AECS-QuikPrep is undoubtedly the World Leaders in Counter-Current,
Centrifugal Partition, Liquid-Liquid, Ionic Liquid Chromatography /
Extraction.
We manufacture both Hydrodynamic CCC
(Planetary CCC, HSCCC, HPCCC, HPL-LC™) and Hydrostatic CCC (Droplet
Centrifugal Partition Chromatography, CPC, HPCPC) at scales from 30 ml
to 100+ litres. We have units in both research laboratories and process
manufacture units throughout the World. We collaborate with Research
Institutes / Universities, for both standard solvents and IONIC LIQUID
BIPHASIC CCC/CPC EXTRACTION & CHROMATOGRAPHY RESEARCH PROGRAMME
We can custom build both CCC & CPC unit’s specific for your
requirements because of our unique modular construction. Options of
different CCC bore or CPC cell / chamber sizes, different volumes on
the same instrument. We can custom design to accommodate your specific
needs, within your budget. Other competitors cannot match our design
and build flexibility. Just ask them and us to custom build to your
specific needs and budget. We will custom build to match your
requirements.
Unique 2D Spiral CCC for UK clientUnique Dual Flow for USA client AECS Exhibiting at CCC 2014
Click thumbnail to expand
PREPARATIVE CHROMATOGRAPHY. CENTRIFUGAL PARTITION & COUNTER CURRENT CHROMATOGRAPHY
Quattro’s enable Instrumental Liquid-Liquid, Preparative Chromatography and Extraction..
Mass Scales:- Laboratory Scale of Milligrams, up to Industrial Scale of Tonnes Per Annum
• Save ~50-90% process chromatography/extraction, solvent/column costs
• Ideal HPLC-MS pre-prep; no column induced degradation or adsorption
• Uniquely allows infinitely polar to infinitely non-polar prep in one run
• Contract laboratory and process method development services available
• Easily scale-up from micro-gram to your tonne plus process chromatography scale
• Orthogonal selectivity options compared to process chromatography by HPLC/Flash/SFC
• No solubility problems; massive range of solvents available
• IL / SFC / SFC-MS / MS / MS-MS / HPLC / HPLC-MS compatible
• High process chromatography mass loading (typically 5 to 40 g per 1 litre capacity)
• Inject up to 10+ % coil volume without excessive band spreading
• High pressure (1000psi+) + high “G” (80-150)(250)(350+) options
• Only manufacturers of both hydrodynamic & hydrostatic CCC
• New dedicated IONIC LIQUID CHROMATOGRAPHY/EXTRACTION CCC/CPC
• New MULTI-COIL, 2D & 3D DUAL-FLOW CCC/CPC extraction options,
WHY YOU NEED QUATTRO CCC / QUATTRO CPC INSTRUMENTS?
LabPrep™ Total volume options from 250ml to 2000ml. Options of 2, 3 or 4 coils per instrument. You can choose multiple volume of coils to suit your specific needs. Coils of same id can be utilised in series, to gain resolution or additional mass injected. Coil id options: 1 mm id, 2 mm id, 4.6 mm id. Coil material options: PTFE, PFA, PEEK, Stainless Steel.
QuikPrep™ & LabPrep™ up to ~2000ml, price depending number coils, coil 1d / volume
PilotPrep™ 4.8 litres CCC. Can work in standard laboratory.
Images of Counter Current Chromatograph and Centrifugal Partition Chromatograph, showing CCC & CPC plus ancillaries at AECS-QuikPrep Ltd Demonstration Laboratory
Note: The Quattro PilotPrep CPC shown can process kilos per day, but still be utilised in a standard laboratory.
Model Type / Volumes Hydrodynamic Counter-Current Chromatography (CCC / HSCCC / HPCCC / HPL-LC™)
Images of Counter Current Chromatographs and Centrifugal Partition Chromatographs
The applications on the left side boxes and given in the various slide shows on right side, represent a fraction od AECS's research experience in CCC & CPC.
AECS-QuikPrep Ltd has been conducting fundamental liquid-liquid chromatography research since 1993. We have innovated many important liquid-liquid chromatography instrument designs. Others have copied, but never bettered our designs, or vaguely approach the safety features of our instrumentation. Most our research has been for confidential research projects, in the main for Pharmaceutical and Agrochemical Companies. Studies for both synthetic and natural products. We have also co-researched with several major International Government Research Laboratories, plus Universities Worldwide
.
Please note our experience dates from 1993 in liquid-liquid chromatography instrument design, manufacture and research. This compares very favourably to many of our present competitor CCC and CPC companies, some of which never even existed in their present form a few years ago. Some are very recent Venture Capital funded start-ups. Others are run by companies that recently purchased failed CPC French competitors. Some competitors sell purified target compound products, that are the equivalent to their clients own products. AECS-QuikPrep Ltd. never does this. Therefore if you need a laboratory, or tonne plus, per annum process method, then come to the experts, AECS-QuikPrep Ltd. No other company comes close to AECS-QuikPrep Ltd's experience in method development, or guarantees never to compete with you on target compound sales.
Quattro HPL-LC™ / HTPrep™ Video (2 bobbins, 4 coils / 3 coil id’s). Door safety mechanism disabled for this demonstration video. Set spin speeds are very constant. The video judder is caused by camera/internet technology.
Novel & New: Sun rotors can be custom made in Stainless Steel or Titanium (for proteins etc).
Instruments
can have, 1 or 2 different id cell (chamber) bores, with pressure
abilities of 1000+ psi, with typically “on-column” loadings of 5 to 40
g per 1 litre. HPCPC is ideal for MAB’s, proteins, peptides &
enzymes, other organic and inorganic extractions or chromatography
purifications.
AECS’s unique multi-block CPC rotor design offers specification options and tolerance to client induced mistakes causing CPC rotor blockage etc., which means significantly less downtime than any competitor. All Quattro CPC built to ISO 9001.
QuikPrep™ & LabPrep CPC™ Laboratory
~250 ml to 2000 ml, Stainless Steel rotor.
PilotPrep™ 4.8 litres. May be used in standard laboratories worldwide.
ProcessPrep™ any volume up to 100's of litres. Must be used in Intrinsically Safe \ Explosion Proof ATEX 1, in Europe
or C1-D1 in the USA or Canada.
Click thumbnail to expand
Model Type / Volumes Hydrostatic CCC, Droplet Centrifugal Partition Chromatography (CPC / HPCPC )
Centrifugal Partition Chromatography Medicinal Cannabinoid Chromatographs performed on our clients’ samples…...
Scale-up Advantages Compared to Competitors
Modular design, and the use of interchangeable components is common in aerospace, car,
electronics etc industry. But only AECS-QuikPrep has employed this concept
to countercurrent chromatography. We did to ensure success in scale-up..
Commercial & Scientific Advantages Compared to Competitors
The AECS brings you both talent and stability.
AECS has been trading as same family-owned Company
for approximately 38 years.
Since 1983 AECS has been doing contract design research for third party
instrument companies. Projects included the design of moving belt
HPLC-MS, HPLC-FID and HPLC-MPD detectors; evaporative light scatter
detectors; the world's first peltier HPLC column air ovens / chillers,
etc. AECS has also helped an USA based HPLC Column Company create
completely new HPLC column / phase product lines. AECS has built
numerous prototype instruments for Blue-Chip International Companies.
AECS built our first Quattro CCC™ in the early 1990's, when Smith Kline
Beecham were not prepared to purchase the then existing CCC / CPC
instrumentation, and placed an open-design Purchase Order with AECS for
what became the Quattro CCC™ Mk I. They like many others, before and
since, trusted AECS's design expertise,
and contracted AECS to build an improved design with regard to both
safety and performance. Since then we have designed and built numerous
custom Quattro HPL-LC™ for many clients. We offer our client’s proven, but ever evolving, commercially relevant
CCC / CPC units. We have over 28 years of worldwide
LLC commercial trading experience.
Please consider
visiting our NEW DEMONSTRATION LABORATORY near Newquay Airport, only 1
hour flight from London Heathrow, and with good connections to many
National & International Airports.
Please consider requesting Dr Leslie Brown visiting you to discuss your larger scale process needs.
If you are interested in collaborative
research, please suggest a topic.We are
particularly interested in high pressure SFE
/ SFC / SFC-MS / L-LC direct to MS
applications, but have a general interest in
many subjects from trace to process quantities.
IMAGES OF QUATTRO CENTRIFUGAL PARTITION CHROMATOGRAPHS FOR PROCESS CHROMATOGRAPHY OF MEDICINAL CANNABINOIDS ETC
First Delivery Equipment PilotPrep USAEarly Stage Install PilotPrep USA. Click thumbnail to expand
Installation with on-site training in your laboratory for one week included in Retail Price for Quattro PiliotPrep™ and ProcessPrep™, is optional at additional cost, for time and expenses, plus allowing for travel restriction.
The modular Process Compatible, ATEX 1 specification in Europe, C1-D1 specification in USA and Canada, QuattroProcessPrepHPCPC start
at 12 litres and go to 100's of litres.
Or consider our Process HPCPC for Simulated Moving Bed use,
standard solvent or IONIC LIQUID solvents or Liquid CO2 use for
CHROMATOGRAPHY OR EFFICIENT EXTRACTION.
Do you need Centrifugal Partition Chromatography Process Scale-up?
Consider using Dr Leslie Brown's lifetime of chromatography experience to help you?
Dr Les Brown has extensive commercial
experience in laboratory and process HPCCC, HPL-LC™, plus CPC and
HPCPC. He has scale-up experience from laboratory to the process Quattro HPCPC™ etc., which will stand you in a highly favoured
position, when you move to potentially multiple tonnes per annum GMP
production. The Quattro CCC™ / HPL-LC™ / CPC™ & HPCPC™ are
respected quality products, with clients throughout the World. Our
unique high backpressure capability will facilitate HPLC-MS, SFE, SFC,
SFC-MS, Ionic Liquid research / process production by either efficient
extraction or chromatography in laboratory + process procedures.
Images of Counter Current Chromatographs and Centrifugal Partition Chromatographs
Click thumbnail to expand
Dr Leslie Brown, MD of AECS-QuikPrep Ltd
Process Chromatography. Be a World Leader with Quattro CPC/CCC (API’s, Cannabinoids etc.)
PLEASE SCROLL DOWN TO VIEW FULL INFORMATION
Click on picture
on left for
"INTRODUCTION"
slide show
scientific
presentation
Click on picture on
left for "Quattro
CCC™ WINE
Research" slide
show scientific
presentation
Click on picture on
left for "Quattro
CCC™ NEEM
Research" slide
show scientific
presentation
Click for General
applications slides
(extra notes in
comments
sections)
Click for Glycoside
applications slides
Click for
Anti-Oxidant
Research
application slides
Click for
comparison
Solid-Liquid and
Liquid-Liquid
Chromatography