COUNTER CURRENT & CENTRIFUGAL PARTITION CHROMATOGRAPHY, PLUS HPLC, IL-LC AND SFC
Together AECS-QuikPrep (UK) and Couturier (France) bring you World Leading products for
High Performance Liquid-Liquid Chromatography™ at scales from micro-gram to tonnes per annum
Milligram to tonnes per annum are available when using the novel, Gyan Flash
Chromatograph which is distributed by AECS.
Existing Biotage, Argonaut, Isco etc Flash Chromatography Instrumentation can be simply
updated to use Jumbo or EasiFlash pumps, cartridges and solid sample injectors. These
innovative, patented Gyan products will often significantly outperform original pumps,
cartridges and injectors, are much easier to use and yet are available from AECS at
extremely competitive prices.
FLASH CHROMATOGRAPHY AT AECS
Your 1st Choice for Preparative and Process Chromatography / Extraction
Unique 360 degree compression allows better resolution and higher sample loading up to 80g
depending on the separation
When you need to scale-up and go to larger flash cartridge sizes, it is important to have a
system which is easy to use, provides the correct compression and allows easy removal of
cartridges after use.
The new patented JumboFlash from Gyan provides all these features plus a variety of columns,
pre-columns and solid sample option.
Patented Design - 360 degree compression
The JumboFlash system uses a unique patented system to solve the compression problem of
larger cartridges. By compressing the cartridge between two stainless steel shells, it is
compressed from all directions.
Conventional systems compress either radially or axially, both of which can compromise
The Gyan system maintains the homogeneity of the packing material improving the
performance of the cartridge.
Turning the bar on the top of the holder applies an axial compression while the two shells
compress the cartridge inwards. The design allows easy removal of the used cartridge after the
run even if has swollen.
How it works
Jumbo Flash consists of a cartridge holder, a steel jacket
and screw compression mechanism. The solvent and
sample inlet is through the centre of the mechanism.
The cartridge is placed on the base.The two wall shells
Pivot from the base and surround the cartridge
The compression mechanism is placed in the top of the
cartridge and connects to the two wall shells as shown to
As the compression mechanism tightens, the shape of the
holder cause it to pull the jacket inwards causing radial
pressure at the same time as applying pressure on the ends
of the column.
To release the cartridge after use, simply reverse the
process and remove the cartridge without any force being
The design allows 80mm diameter cartridges of different lengths to be accommodated in the
same holder. In addition to standard lengths, custom bed depths are available to order thus
optimising separations and saving money by not buying unnecessary silica.
Equipment to pack columns of larger than 2 inch bore requires a large one-off cost, plus
requires the purchase of HPLC phase as a consumable.
For samples that need to be pre-absorbed on silica, the Sample cartridges can be used.
These are available with special holders that fit directly on to the JumboFlash holder with a
zero dead volume
System Part Numbers
JF0001 Holder for large dimension cartridges (80mm i.d.) Uses both radial and axial
compression and allows easy removal of swollen cartridges. Used to purify up to 40g
A special patented frit system ensures that the sample is placed uniformly on the column,
optimising the conditions for a good separation
Ease of use
A four way valve introduces liquid samples on to the top of the column without the need to
stop the pump.
Using EasiSoft software it is possible to scale up directly from separations made with smaller
JumboFlash is quickly being developed further. For further details, please register your
interest by clicking here We will be pleased to discuss you specific requirements and provide
AECS can offer "Total Preparative Solutions™" packages, and can therefore assist you in
your choice of the best preparative technology, be it Flash Chromatography, Preparative /
Process HPLC, or HSCCC, or even maybe a two / three dimensional combination.
AECS can also offer contract method development or final product preparation to non-GMP or
For additional information on the Jumbo Flash contact us at AECS.
Jumbo Flash : Patented Axial & Radial Compression Improves Efficiency And
Allows Up To 80g Injections Now..... 250+ g Soon !!!